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TargetDual specificity mitogen-activated protein kinase kinase 3
LigandBDBM50375668
Substrate/Competitorn/a
Meas. Tech.ChEMBL_473817 (CHEMBL921077)
IC50>1000±n/a nM
Citation Fedorov, OMarsden, BPogacic, VRellos, PMüller, SBullock, ANSchwaller, JSundström, MKnapp, S A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. Proc Natl Acad Sci U S A104:20523-8 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Dual specificity mitogen-activated protein kinase kinase 3
Name:Dual specificity mitogen-activated protein kinase kinase 3
Synonyms:Dual specificity mitogen-activated protein kinase kinase 3 | MAP kinase kinase 3 | MAP2K3 | MAPK/ERK kinase 3 | MAPK/ERK kinase 3 (MEK3) | MAPKK 3 | MEK3 | MKK3 | MP2K3_HUMAN | PRKMK3 | SKK2
Type:Protein
Mol. Mass.:39321.50
Organism:Homo sapiens (Human)
Description:n/a
Residue:347
Sequence:
MESPASSQPASMPQSKGKSKRKKDLRISCMSKPPAPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50375668
n/a
NameBDBM50375668
Synonyms:CHEMBL259526
TypeSmall organic molecule
Emp. Form.C3H4N2
Mol. Mass.68.0773
SMILESCC=NC#N |w:1.0|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: