| Reaction Details |
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 | Report a problem with these data |
| Target | Yersiniabactin siderophore biosynthetic protein |
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| Ligand | BDBM50376538 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_477384 (CHEMBL928172) |
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| IC50 | 200±n/a nM |
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| Citation |  Stirrett, KL; Ferreras, JA; Jayaprakash, V; Sinha, BN; Ren, T; Quadri, LE Small molecules with structural similarities to siderophores as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis. Bioorg Med Chem Lett18:2662-8 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Yersiniabactin siderophore biosynthetic protein |
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| Name: | Yersiniabactin siderophore biosynthetic protein |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57211.99 |
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| Organism: | Yersinia pestis CA88-4125 |
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| Description: | ChEMBL_477384 |
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| Residue: | 525 |
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| Sequence: | MNSSFESLIEQYPLPIAEQLRHWAARYASRIAVVDAKGSLTYSALDAQVDELAAGLSSLG
LRSGEHVIVQLPNDNAFVTLLFALLRLGVIPVLAMPSQRALDIDALIELAQPVAYVIHGE
NHAELARQMAHKHACLRHVLVAGETVSDDFTPLFSLHGERQAWPQPDVSATALLLLSGGT
TGTPKLIPRRHADYSYNFSASAELCGISQQSVYLAVLPVAHNFPLACPGILGTLACGGKV
VLTDSASCDEVMPLIAQERVTHVALVPALAQLWVQAREWEDSDLSSLRVIQAGGARLDPT
LAEQVIATFDCTLQQVFGMAEGLLCFTRLDDPHATILHSQGRPLSPLDEIRIVDQDENDV
APGETGQLLTRGPYTISGYYRAPAHNAQAFTAQGFYRTGDNVRLDEVGNLHVEGRIKEQI
NRAGEKIAAAEVESALLRLAEVQDCAVVAAPDTLLGERICAFIIAQQVPTDYQQLRQQLT
RMGLSAWKIPDQIEFLDHWPLTAVGKIDKKRLTALAVDRYRHSAQ
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| BDBM50376538 |
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| n/a |
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| Name | BDBM50376538 |
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| Synonyms: | CHEMBL404731 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H21N3O3S |
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| Mol. Mass. | 419.496 |
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| SMILES | COc1ccc(NC(=S)N2N=C(C[C@H]2c2ccccc2O)c2ccccc2O)cc1 |c:10| |
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| Structure | 
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