| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphotransferase |
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| Ligand | BDBM50173794 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_477724 (CHEMBL927022) |
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| IC50 | 810±n/a nM |
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| Citation |  Sanz-Rodríguez, CE; Concepción, JL; Pekerar, S; Oldfield, E; Urbina, JA Bisphosphonates as inhibitors of Trypanosoma cruzi hexokinase: kinetic and metabolic studies. J Biol Chem282:12377-87 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phosphotransferase |
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| Name: | Phosphotransferase |
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| Synonyms: | Hexokinase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52180.94 |
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| Organism: | Trypanosoma cruzi |
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| Description: | ChEMBL_330068 |
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| Residue: | 471 |
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| Sequence: | MSARLNNLLQHIAVKDKDSDTMRHLKQRMALASLANQFTVGKDHLKQLMLYMVHQMIEGL
EGRESTLRMLPSYVYKTDPSKATGVFYALDLGGTNFRVLRVTCKEGRVADRVDAKFVIPQ
QALQGTAEDLFGFIAQSVKKMMEQKAPEDLNRTVPLGFTFSFPTEQKGVDHGFLIKWTKG
FSTRGVEGKDVVELLQKALKRMEVKVKVVALCNDTVGTLITNYFFDPDTQVGVIIGTGSN
ACYFEDAYAVTKEPSVAARGTTQTPINMECGNFDSKYKFVLPVTAYDEAMDAVTPNRNFQ
TQEKMVSGMYLGEISRRMIAHLAELHCLPSALASKMAKPWSFETKFMGMISADRMPGLQF
TRQVFQELFQVDVTDVADLHVIRDVCCLVRGRAAQISAMFCSAPLVKTRKEGRATVAIDG
SVFEKTPSFRRLLQQNMNAILGPGCDVTTALARDGSGIGAAFISALVVNDK
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| BDBM50173794 |
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| n/a |
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| Name | BDBM50173794 |
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| Synonyms: | (3',4'-difluorobiphenyl-3-ylamino)methylenediphosphonic acid | CHEMBL194800 | [(3',4'-Difluoro-biphenyl-3-ylamino)-phosphono-methyl]-phosphonic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C13H13F2NO6P2 |
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| Mol. Mass. | 379.1898 |
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| SMILES | OP(O)(=O)C(Nc1cccc(c1)-c1ccc(F)c(F)c1)P(O)(O)=O |
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| Structure | 
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