| Reaction Details |
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 | Report a problem with these data |
| Target | 4-aminobutyrate aminotransferase, mitochondrial |
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| Ligand | BDBM50376755 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_477747 (CHEMBL939957) |
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| IC50 | >5000000±n/a nM |
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| Citation |  Clift, MD; Silverman, RB Synthesis and evaluation of novel aromatic substrates and competitive inhibitors of GABA aminotransferase. Bioorg Med Chem Lett18:3122-5 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 4-aminobutyrate aminotransferase, mitochondrial |
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| Name: | 4-aminobutyrate aminotransferase, mitochondrial |
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| Synonyms: | (S)-3-amino-2-methylpropionate transaminase | 4-aminobutyrate aminotransferase, mitochondrial | ABAT | GABA aminotransferase | GABA transaminase | GABA-AT | GABA-T | GABAT | GABT_HUMAN | Gamma-amino-N-butyrate transaminase | L-AIBAT |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56449.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1459248 |
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| Residue: | 500 |
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| Sequence: | MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMK
QLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQ
NASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYR
SKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPS
FDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGG
DNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMM
TGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLL
DLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVF
RDHHAHLFLNIFSDILADFK
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| BDBM50376755 |
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| n/a |
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| Name | BDBM50376755 |
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| Synonyms: | CHEMBL535643 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H11NO2 |
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| Mol. Mass. | 165.1891 |
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| SMILES | NCc1cccc(CC(O)=O)c1 |
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| Structure | 
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