Reaction Details |
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Target | C5a anaphylatoxin chemotactic receptor 1 |
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Ligand | BDBM50376803 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_477917 (CHEMBL923542) |
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Ki | 9.70±n/a nM |
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Citation | Barbay, JK; Gong, Y; Buntinx, M; Li, J; Claes, C; Hornby, PJ; Van Lommen, G; Van Wauwe, J; He, W Synthesis and characterization of 5,6,7,8-tetrahydroquinoline C5a receptor antagonists. Bioorg Med Chem Lett18:2544-8 (2008) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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C5a anaphylatoxin chemotactic receptor 1 |
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Name: | C5a anaphylatoxin chemotactic receptor 1 |
Synonyms: | C5AR | C5AR1 | C5AR1_HUMAN | C5R1 | C5a anaphylatoxin chemotactic receptor | C5a anaphylatoxin chemotactic receptor (C5aR) | C5a-R | CD_antigen=CD88 |
Type: | Enzyme |
Mol. Mass.: | 39347.68 |
Organism: | Homo sapiens (Human) |
Description: | P21730 |
Residue: | 350 |
Sequence: | MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVW
VTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNM
YASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREE
YFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKT
LKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIY
VVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
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BDBM50376803 |
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n/a |
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Name | BDBM50376803 |
Synonyms: | CHEMBL262330 |
Type | Small organic molecule |
Emp. Form. | C30H33F3N2O |
Mol. Mass. | 494.591 |
SMILES | CCc1cccc(CC)c1-c1cc(OC)c2C(CCCc2n1)N1CCc2cccc(c2C1)C(F)(F)F |w:16.24| |
Structure |
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