| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50377502 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_479704 (CHEMBL933568) |
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| Ki | 303±n/a nM |
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| Citation |  Gillespie, RJ; Cliffe, IA; Dawson, CE; Dourish, CT; Gaur, S; Giles, PR; Jordan, AM; Knight, AR; Lawrence, A; Lerpiniere, J; Misra, A; Pratt, RM; Todd, RS; Upton, R; Weiss, SM; Williamson, DS Antagonists of the human adenosine A2A receptor. Part 2: Design and synthesis of 4-arylthieno[3,2-d]pyrimidine derivatives. Bioorg Med Chem Lett18:2920-3 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50377502 |
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| n/a |
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| Name | BDBM50377502 |
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| Synonyms: | CHEMBL406315 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H12N4S2 |
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| Mol. Mass. | 276.38 |
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| SMILES | CN(C)c1nc(-c2nc(C)cs2)c2sccc2n1 |
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| Structure | 
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