| Reaction Details |
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 | Report a problem with these data |
| Target | IAG-nucleoside hydrolase |
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| Ligand | BDBM50260480 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_531315 (CHEMBL989727) |
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| Ki | 4500000±n/a nM |
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| Citation |  Goeminne, A; McNaughton, M; Bal, G; Surpateanu, G; Van Der Veken, P; De Prol, S; Versées, W; Steyaert, J; Haemers, A; Augustyns, K Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors. Eur J Med Chem43:315-26 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| IAG-nucleoside hydrolase |
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| Name: | IAG-nucleoside hydrolase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36316.77 |
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| Organism: | Trypanosoma vivax |
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| Description: | ChEMBL_531315 |
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| Residue: | 327 |
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| Sequence: | MAKNVVLDHDGNLDDFVAMVLLASNTEKVRLIGALCTDADCFVENGFNVTGKIMCLMHNN
MNLPLFPIGKSAATAVNPFPKEWRCLAKNMDDMPILNIPENVELWDKIKAENEKYEGQQL
LADLVMNSEEKVTICVTGPLSNVAWCIDKYGEKFTSKVEECVIMGGAVDVRGNVFLPSTD
GTAEWNIYWDPASAKTVFGCPGLRRIMFSLDSTNTVPVRSPYVQRFGEQTNFLLSILVGT
MWAMCTHCELLRDGDGYYAWDALTAAYVVDQKVANVDPVPIDVVVDKQPNEGATVRTDAE
KYPLTFVARNPEAEFFLDMLLRSARAC
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| BDBM50260480 |
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| n/a |
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| Name | BDBM50260480 |
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| Synonyms: | (2R,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-tetrahydro-2-furancarboxamide | CHEMBL455563 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H11NO5 |
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| Mol. Mass. | 177.1552 |
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| SMILES | NC(=O)[C@@H]1O[C@H](CO)[C@H](O)[C@@H]1O |r| |
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| Structure | 
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