Reaction Details | |||
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Target | Somatostatin receptor type 1 | ||
Ligand | BDBM50136824 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_532742 (CHEMBL972316) | ||
IC50 | 27±n/a nM | ||
Citation | Erchegyi, J; Grace, CR; Samant, M; Cescato, R; Piccand, V; Riek, R; Reubi, JC; Rivier, JE Ring size of somatostatin analogues (ODT-8) modulates receptor selectivity and binding affinity. J Med Chem51:2668-75 (2008) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Somatostatin receptor type 1 | |||
Name: | Somatostatin receptor type 1 | ||
Synonyms: | SOMATOSTATIN SST1 | SRIF-2 | SS-1-R | SS1-R | SS1R | SSR1_HUMAN | SSTR1 | Somatostatin receptor type 1 (SSTR1) | ||
Type: | Enzyme | ||
Mol. Mass.: | 42692.81 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P30872 | ||
Residue: | 391 | ||
Sequence: |
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BDBM50136824 | |||
n/a | |||
Name | BDBM50136824 | ||
Synonyms: | (4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl)methyl)-25-amino-13-(4-aminobutyl)-7,19,22-tribenzyl-10-((R)-1-hydroxyethyl)-6,9,12,15,18,21,24-heptaoxo-1,2-dithia-5,8,11,14,17,20,23-heptaazacyclohexacosane-4-carboxylic acid | (S)-25-Amino-13-(4-amino-butyl)-7,19,22-tribenzyl-10-((R)-1-hydroxy-ethyl)-16-(1H-indol-3-ylmethyl)-6,12,15,18-tetra(S)-oxo-9,21-di(R)-oxo-24-oxo-1,2-dithia-5,8,11,14,17,20,23-heptaaza-cyclohexacosane-4-carboxylic acid | CHEMBL266477 | H-c(Cys3-Phe6-Phe7-DTrp8-Lys9-Thr10-Phe11-Cys14)-OH | ODT-8 | ||
Type | Small organic molecule | ||
Emp. Form. | C54H66N10O10S2 | ||
Mol. Mass. | 1079.293 | ||
SMILES | C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O | ||
Structure |