| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 2 |
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| Ligand | BDBM50261391 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_532743 (CHEMBL972317) |
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| IC50 | 11±n/a nM |
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| Citation |  Erchegyi, J; Grace, CR; Samant, M; Cescato, R; Piccand, V; Riek, R; Reubi, JC; Rivier, JE Ring size of somatostatin analogues (ODT-8) modulates receptor selectivity and binding affinity. J Med Chem51:2668-75 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 2 |
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| Name: | Somatostatin receptor type 2 |
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| Synonyms: | SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 41344.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30874 |
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| Residue: | 369 |
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| Sequence: | MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCG
NTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMT
VDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIY
AGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGI
RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVL
TYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTL
LNGDLQTSI
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| BDBM50261391 |
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| n/a |
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| Name | BDBM50261391 |
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| Synonyms: | (4S,7S,10S,13S,16R,19S,22S,25S)-25-Amino-13-(4-amino-butyl)-7,19,22-tribenzyl-10-((R)-1-hydroxy-ethyl)-16-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24-heptaoxo-1,2-dithia-5,8,11,14,17,20,23-heptaaza-cyclohexacosane-4-carboxylic acid | CHEMBL501776 |
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| Type | Small organic molecule |
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| Emp. Form. | C54H66N10O10S2 |
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| Mol. Mass. | 1079.293 |
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| SMILES | C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](N)CSSC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O |r| |
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| Structure | 
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