| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M4 |
|---|
| Ligand | BDBM50271706 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_556757 (CHEMBL960608) |
|---|
| Ki | >500±n/a nM |
|---|
| Citation |  Nichols, DE; Frescas, SP; Chemel, BR; Rehder, KS; Zhong, D; Lewin, AH High specific activity tritium-labeled N-(2-methoxybenzyl)-2,5-dimethoxy-4-iodophenethylamine (INBMeO): a high-affinity 5-HT2A receptor-selective agonist radioligand. Bioorg Med Chem16:6116-23 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M4 |
|---|
| Name: | Muscarinic acetylcholine receptor M4 |
|---|
| Synonyms: | ACM4_HUMAN | CHRM4 | Cholinergic, muscarinic M4 | Muscarinic acetylcholine receptor | Muscarinic acetylcholine receptor M2 and M4 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 53079.31 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Cholinergic, muscarinic M4 CHRM4 HUMAN M3::P08173 |
|---|
| Residue: | 479 |
|---|
| Sequence: | MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGS
ATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIV
PATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMV
LVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR
|
|
|
|---|
| BDBM50271706 |
|---|
| n/a |
|---|
| Name | BDBM50271706 |
|---|
| Synonyms: | CHEMBL482496 | N-(2-[3H-OCH3]benzyl)-2-(2-[3H-OCH3]-5-methoxy-4-iodophenyl)ethylamine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H22INO3 |
|---|
| Mol. Mass. | 427.2767 |
|---|
| SMILES | COc1ccccc1CNCCc1cc(OC)c(I)cc1OC |
|---|
| Structure | 
|
|---|
Search and Browse
