Ki Summary

Reaction Details

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Target

Ectonucleoside triphosphate diphosphohydrolase 2

Ligand

BDBM50029031

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_514529 (CHEMBL968883)

24200±n/a nM

Citation

Brunschweiger, A; Iqbal, J; Umbach, F; Scheiff, AB; Munkonda, MN; Sévigny, J; Knowles, AF; Müller, CE Selective nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) inhibitors: nucleotide mimetics derived from uridine-5'-carboxamide. J Med Chem51:4518-28 (2008) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Ectonucleoside triphosphate diphosphohydrolase 2

Name:

Ectonucleoside triphosphate diphosphohydrolase 2

Synonyms:

Cd39l1 | ENTP2_RAT | Entpd2

Type:

PROTEIN

Mol. Mass.:

54401.50

Organism:

Rattus norvegicus

Description:

ChEMBL_612639

Residue:

495

Sequence:

MAGKLVSLVPPLLLAAAGLTGLLLLCVPTQDVREPPALKYGIVLDAGSSHTSMFVYKWPA
DKENDTGIVGQHSSCDVQGGGISSYANDPSKAGQSLVRCLEQALRDVPRDRHASTPLYLG
ATAGMRPFNLTSPEATARVLEAVTQTLTQYPFDFRGARILSGQDEGVFGWVTANYLLENF
IKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSEDPGNEVHLRLYGQHYRVYTHSF
LCYGRDQILLRLLASALQIHRFHPCWPKGYSTQVLLQEVYQSPCTMGQRPRAFNGSAIVS
LSGTSNATLCRDLVSRLFNISSCPFSQCSFNGVFQPPVAGNFIAFSAFYYTVDFLTTVMG
LPVGTLKQLEEATEITCNQTWTELQARVPGQKTRLADYCAVAMFIHQLLSRGYHFDERSF
REVVFQKKAADTAVGWALGYMLNLTNLIPADLPGLRKGTHFSSWVALLLLFTVLILAALV
LLLRQVRSAKSPGAL

BDBM50029031

n/a

Name

BDBM50029031

Synonyms:

1-Amino-4-{4-[4-chloro-6-(3-sulfo-phenylamino)-[1,3,5]triazin-2-ylamino]-3-sulfo-phenylamino}-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonic acid1-Amino-4-{4-[4-chloro-6-(4-sulfo-phenylamino)-[1,3,5]triazin-2-ylamino]-3-sulfo-phenylamino}-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonic acid | CHEMBL223344 | CID44285648 | basilen blue | cibacron blue (mixer, meta and para isomers

Type

Small organic molecule

Emp. Form.

C29H17ClN7O11S3

Mol. Mass.

771.135

SMILES

Nc1c(cc(Nc2ccc(Nc3nc(Cl)nc(Nc4cccc(c4)S([O-])(=O)=O)n3)c(c2)S([O-])(=O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O

Structure