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TargetEctonucleoside triphosphate diphosphohydrolase 2
LigandBDBM50262422
Substrate/Competitorn/a
Meas. Tech.ChEMBL_514529
Ki 44200±n/a nM
Citation Brunschweiger AIqbal JUmbach FScheiff ABMunkonda MNSévigny JKnowles AFMüller CE Selective nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) inhibitors: nucleotide mimetics derived from uridine-5'-carboxamide. J Med Chem 51:4518-28 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Ectonucleoside triphosphate diphosphohydrolase 2
Name:Ectonucleoside triphosphate diphosphohydrolase 2
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:54401.50
Organism:Rattus norvegicus
Description:ChEMBL_612639
Residue:495
Sequence:
MAGKLVSLVPPLLLAAAGLTGLLLLCVPTQDVREPPALKYGIVLDAGSSHTSMFVYKWPA
DKENDTGIVGQHSSCDVQGGGISSYANDPSKAGQSLVRCLEQALRDVPRDRHASTPLYLG
ATAGMRPFNLTSPEATARVLEAVTQTLTQYPFDFRGARILSGQDEGVFGWVTANYLLENF
IKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSEDPGNEVHLRLYGQHYRVYTHSF
LCYGRDQILLRLLASALQIHRFHPCWPKGYSTQVLLQEVYQSPCTMGQRPRAFNGSAIVS
LSGTSNATLCRDLVSRLFNISSCPFSQCSFNGVFQPPVAGNFIAFSAFYYTVDFLTTVMG
LPVGTLKQLEEATEITCNQTWTELQARVPGQKTRLADYCAVAMFIHQLLSRGYHFDERSF
REVVFQKKAADTAVGWALGYMLNLTNLIPADLPGLRKGTHFSSWVALLLLFTVLILAALV
LLLRQVRSAKSPGAL
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  Blast E-value cutoff:
BDBM50262422
n/a
NameBDBM50262422
Synonyms:CHEMBL477339 | sodium (E)-4-((3-formyl-4-hydroxy-5-methyl-2-(phosphonatooxymethyl)phenyl)diazenyl)benzene-1,3-disulfonate
TypeSmall organic molecule
Emp. Form.C15H11N2O12PS2
Mol. Mass.506.36
SMILESCc1cc(N=Nc2ccc(cc2S([O-])(=O)=O)S([O-])(=O)=O)c(COP([O-])([O-])=O)c(C=O)c1O |w:4.3|
Structure
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