| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin G/H synthase 1 |
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| Ligand | BDBM50245466 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_511829 (CHEMBL969892) |
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| IC50 | 20±n/a nM |
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| Citation |  Scholz, M; Ulbrich, HK; Dannhardt, G Investigations concerning the COX/5-LOX inhibiting and hydroxyl radical scavenging potencies of novel 4,5-diaryl isoselenazoles. Eur J Med Chem43:1152-9 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin G/H synthase 1 |
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| Name: | Prostaglandin G/H synthase 1 |
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| Synonyms: | COX-1 | COX1 | Cyclooxygenase | Cyclooxygenase-1 | PGH1_BOVIN | PTGS1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 68814.10 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_547440 |
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| Residue: | 600 |
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| Sequence: | MSRQGISLRFPLLLLLLSPSPVLPADPGAPAPVNPCCYYPCQHQGICVRFGLDRYQCDCT
RTGYYGPNCTIPEIWTWLRTTLRPSPSFVHFLLTHGRWLWDFVNATFIRDKLMRLVLTVR
SNLIPSPPTYNVAHDYISWESFSNVSYYTRILPSVPRDCPTPMGTKGKKQLPDAEFLSRR
FLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLER
QYQLRLFKDGKLKYQMLNGEVYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMV
YATIWLREHNRVCDLLKAEHPTWGDEQLFQTARLILIGETIKIVIEEYVQQLSGYFLQLK
FDPELLFGAQFQYRNRIAMEFNQLYHWHPLMPDSFRVGPQDYSYEQFLFNTSMLVDYGVE
ALVDAFSRQPAGRIGGGRNIDHHILHVAVDVIKESRELRLQPFNEYRKRFGMKPYTSFQE
LTGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEMGAPFSLKGLLGNPIC
SPEYWKASTFGGDVGFNLVKTATLKKLVCLNTKTCPYVSFHVPDPHREDRPGVERPPTEL
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| BDBM50245466 |
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| n/a |
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| Name | BDBM50245466 |
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| Synonyms: | 4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-1,2-selenazole | CHEMBL471501 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12ClNOSe |
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| Mol. Mass. | 348.69 |
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| SMILES | COc1ccc(cc1)-c1[se]ncc1-c1ccc(Cl)cc1 |
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| Structure | 
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