Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM50176263 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_558748 (CHEMBL1019877) |
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Ki | 2900±n/a nM |
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Citation | Wentland, MP; Lou, R; Lu, Q; Bu, Y; VanAlstine, MA; Cohen, DJ; Bidlack, JM Syntheses and opioid receptor binding properties of carboxamido-substituted opioids. Bioorg Med Chem Lett19:203-8 (2008) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM50176263 |
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n/a |
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Name | BDBM50176263 |
Synonyms: | 3-((1R,2R)-2-((dimethylamino)methyl)-1-hydroxycyclohexyl)phenol | CHEMBL1400 | O-DESMETHYL TRAMADOL | Ultracet | rel-3-((1R,2R)-2-((dimethylamino)methyl)-1-hydroxycyclohexyl)phenol |
Type | Small organic molecule |
Emp. Form. | C15H23NO2 |
Mol. Mass. | 249.3486 |
SMILES | CN(C)C[C@H]1CCCC[C@]1(O)c1cccc(O)c1 |r| |
Structure |
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