| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier family 22 member 1 |
|---|
| Ligand | BDBM25761 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_534654 (CHEMBL994103) |
|---|
| IC50 | 63200±n/a nM |
|---|
| Citation |  Ahlin, G; Karlsson, J; Pedersen, JM; Gustavsson, L; Larsson, R; Matsson, P; Norinder, U; Bergström, CA; Artursson, P Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. J Med Chem51:5932-42 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Solute carrier family 22 member 1 |
|---|
| Name: | Solute carrier family 22 member 1 |
|---|
| Synonyms: | Adrenergic Alpha | OCT1 | Organic cation transporter 1 | S22A1_HUMAN | SLC22A1 | Solute carrier family 22 member 1 | hOCT1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 61154.85 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Adrenergic Alpha 0 HUMAN::O15245 |
|---|
| Residue: | 554 |
|---|
| Sequence: | MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT
PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN
TIYLKVQTSEPSGT
|
|
|
|---|
| BDBM25761 |
|---|
| n/a |
|---|
| Name | BDBM25761 |
|---|
| Synonyms: | Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-) | PROPRANOLOL, d | PROPRANOLOL, l- | PROPRANOLOL,(+) | PROPRANOLOL,(-) | Propanolol | Propanolol,(+/-) | Propranolol | [2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H21NO2 |
|---|
| Mol. Mass. | 259.3434 |
|---|
| SMILES | CC(C)NCC(O)COc1cccc2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
