Reaction Details | |||
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Target | Solute carrier family 22 member 1 | ||
Ligand | BDBM50001955 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_534654 (CHEMBL994103) | ||
IC50 | 20800±n/a nM | ||
Citation | Ahlin, G; Karlsson, J; Pedersen, JM; Gustavsson, L; Larsson, R; Matsson, P; Norinder, U; Bergström, CA; Artursson, P Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. J Med Chem51:5932-42 (2008) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Solute carrier family 22 member 1 | |||
Name: | Solute carrier family 22 member 1 | ||
Synonyms: | Adrenergic Alpha | OCT1 | Organic cation transporter 1 | S22A1_HUMAN | SLC22A1 | Solute carrier family 22 member 1 | hOCT1 | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 61154.85 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Adrenergic Alpha 0 HUMAN::O15245 | ||
Residue: | 554 | ||
Sequence: |
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BDBM50001955 | |||
n/a | |||
Name | BDBM50001955 | ||
Synonyms: | (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO) | (Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine) | (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine) | (R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine) | (apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine) | 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine) | APOKYN | APOMORPHINE | APOMORPHINE HYDROCHLORIDE | APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | CHEMBL53 | ||
Type | Small organic molecule | ||
Emp. Form. | C17H17NO2 | ||
Mol. Mass. | 267.3224 | ||
SMILES | CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| | ||
Structure |