| Reaction Details |
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 | Report a problem with these data |
| Target | Dihydroorotate dehydrogenase (fumarate) |
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| Ligand | BDBM50206334 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_519009 (CHEMBL942570) |
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| IC50 | >10000±n/a nM |
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| Citation |  Dong, CK; Patel, V; Yang, JC; Dvorin, JD; Duraisingh, MT; Clardy, J; Wirth, DF Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors. Bioorg Med Chem Lett19:972-5 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dihydroorotate dehydrogenase (fumarate) |
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| Name: | Dihydroorotate dehydrogenase (fumarate) |
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| Synonyms: | Dihydroorotate dehydrogenase | PYRD_YEAST | URA1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 34799.00 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | P28272 |
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| Residue: | 314 |
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| Sequence: | MTASLTTKFLNNTYENPFMNASGVHCMTTQELDELANSKAGAFITKSATTLEREGNPEPR
YISVPLGSINSMGLPNEGIDYYLSYVLNRQKNYPDAPAIFFSVAGMSIDENLNLLRKIQD
SEFNGITELNLSCPNVPGKPQVAYDFDLTKETLEKVFAFFKKPLGVKLPPYFDFAHFDIM
AKILNEFPLAYVNSINSIGNGLFIDVEKESVVVKPKNGFGGIGGEYVKPTALANVRAFYT
RLRPEIKVIGTGGIKSGKDAFEHLLCGASMLQIGTELQKEGVKIFERIEKELKDIMEAKG
YTSIDQFRGKLNSI
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| BDBM50206334 |
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| n/a |
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| Name | BDBM50206334 |
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| Synonyms: | CHEMBL397686 | Diphenylene iodonium chloride | dibenziodolium chloride |
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| Type | Small organic molecule |
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| Emp. Form. | C12H8I |
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| Mol. Mass. | 279.0958 |
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| SMILES | [I+]1c2ccccc2-c2ccccc12 |
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| Structure | 
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