| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50278472 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_565043 (CHEMBL959186) |
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| Ki | 12300±n/a nM |
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| Citation |  Behrenswerth, A; Volz, N; Toräng, J; Hinz, S; Bräse, S; Müller, CE Synthesis and pharmacological evaluation of coumarin derivatives as cannabinoid receptor antagonists and inverse agonists. Bioorg Med Chem17:2842-51 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52856.55 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P20272 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50278472 |
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| n/a |
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| Name | BDBM50278472 |
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| Synonyms: | 5-Methoxy-3-(2-methoxybenzyl)-8-methyl-2Hchromen-2-one | CHEMBL470017 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18O4 |
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| Mol. Mass. | 310.3438 |
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| SMILES | COc1ccccc1Cc1cc2c(OC)ccc(C)c2oc1=O |
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| Structure | 
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