| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50258571 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_523689 (CHEMBL998034) |
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| Ki | 69.8±n/a nM |
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| Citation |  Manera, C; Saccomanni, G; Adinolfi, B; Benetti, V; Ligresti, A; Cascio, MG; Tuccinardi, T; Lucchesi, V; Martinelli, A; Nieri, P; Masini, E; Di Marzo, V; Ferrarini, PL Rational design, synthesis, and pharmacological properties of new 1,8-naphthyridin-2(1H)-on-3-carboxamide derivatives as highly selective cannabinoid-2 receptor agonists. J Med Chem52:3644-51 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50258571 |
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| n/a |
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| Name | BDBM50258571 |
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| Synonyms: | CHEMBL466429 | N-(4-Fluorophenylethyl)-1-benzyl-1,8-naphthyridin-2(1H)-on-3-carboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C24H20FN3O2 |
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| Mol. Mass. | 401.4329 |
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| SMILES | Fc1ccc(CCNC(=O)c2cc3cccnc3n(Cc3ccccc3)c2=O)cc1 |
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| Structure | 
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