| Reaction Details |
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 | Report a problem with these data |
| Target | Glyoxalase I |
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| Ligand | BDBM50294134 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_571116 (CHEMBL1030416) |
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| Ki | 6.17±n/a nM |
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| Citation |  More, SS; Vince, R Inhibition of glyoxalase I: the first low-nanomolar tight-binding inhibitors. J Med Chem52:4650-6 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glyoxalase I |
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| Name: | Glyoxalase I |
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| Synonyms: | GLO1 | LGUL_YEAST | Lactoylglutathione lyase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37210.98 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | ChEMBL_571116 |
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| Residue: | 326 |
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| Sequence: | MSTDSTRYPIQIEKASNDPTLLLNHTCLRVKDPARTVKFYTEHFGMKLLSRKDFEEAKFS
LYFLSFPKDDIPKNKNGEPDVFSAHGVLELTHNWGTEKNPDYKINNGNEEPHRGFGHICF
SVSDINKTCEELESQGVKFKKRLSEGRQKDIAFALGPDGYWIELITYSREGQEYPKGSVG
NKFNHTMIRIKNPTRSLEFYQNVLGMKLLRTSEHESAKFTLYFLGYGVPKTDSVFSCESV
LELTHNWGTENDPNFHYHNGNSEPQGYGHICISCDDAGALCKEIEVKYGDKIQWSPKFNQ
GRMKNIAFLKDPDGYSIEVVPHGLIA
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| BDBM50294134 |
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| n/a |
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| Name | BDBM50294134 |
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| Synonyms: | (S)-2-Amino-4-{(S)-3-[(4-bromo-phenyl)-hydroxy-carbamoyl]-1-carboxyaminocarbonyl-propylcarbamoyl}-butyric acid TFA | CHEMBL549339 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H23BrN4O8 |
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| Mol. Mass. | 503.301 |
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| SMILES | N[C@@H](CCC(=O)N[C@@H](CCC(=O)N(O)c1ccc(Br)cc1)C(=O)NCC(O)=O)C(O)=O |r| |
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| Structure | 
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