| Reaction Details |
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 | Report a problem with these data |
| Target | Inosine-5'-monophosphate dehydrogenase |
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| Ligand | BDBM50378053 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_571746 (CHEMBL1032991) |
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| IC50 | >5000±n/a nM |
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| Citation |  Maurya, SK; Gollapalli, DR; Kirubakaran, S; Zhang, M; Johnson, CR; Benjamin, NN; Hedstrom, L; Cuny, GD Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase. J Med Chem52:4623-30 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Inosine-5'-monophosphate dehydrogenase |
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| Name: | Inosine-5'-monophosphate dehydrogenase |
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| Synonyms: | Cgd6_20 protein | IMDH_CRYPV | Inosine-5'-monophosphate dehydrogenase, probable | Inosine-5-monophosphate dehydrogenase (IMPDH) |
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| Type: | Protein |
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| Mol. Mass.: | 43076.80 |
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| Organism: | Cryptosporidium parvum |
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| Description: | Q8T6T2 |
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| Residue: | 400 |
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| Sequence: | MGTKNIGKGLTFEDILLVPNYSEVLPREVSLETKLTKNVSLKIPLISSAMDTVTEHLMAV
GMARLGGIGIIHKNMDMESQVNEVLKVKNWISNLEKNESTPDQNLDKESTDGKDTKSNNN
IDAYSNENLDNKGRLRVGAAIGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIK
SKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSS
VASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKYYR
GMGSVGAMKSGSGDRYFQEKRPENKMVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGYLG
SASIEELWKKSSYVEITTSGLRESHVHDVEIVKEVMNYSK
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| BDBM50378053 |
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| n/a |
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| Name | BDBM50378053 |
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| Synonyms: | CHEMBL564117 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18ClNO2 |
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| Mol. Mass. | 351.826 |
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| SMILES | Clc1ccc(NC(=O)C(Oc2cccc3ccccc23)C2CC2)cc1 |
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| Structure | 
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