Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM50294427 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_575378 (CHEMBL1027052) |
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Ki | 0.190000±n/a nM |
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Citation | Nagase, H; Osa, Y; Nemoto, T; Fujii, H; Imai, M; Nakamura, T; Kanemasa, T; Kato, A; Gouda, H; Hirono, S Design and synthesis of novel delta opioid receptor agonists and their pharmacologies. Bioorg Med Chem Lett19:2792-5 (2009) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40465.04 |
Organism: | Rattus norvegicus (rat) |
Description: | Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor. |
Residue: | 372 |
Sequence: | MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTAC
TPSDGPGGGAAA
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BDBM50294427 |
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n/a |
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Name | BDBM50294427 |
Synonyms: | CHEMBL564538 | SN-23 |
Type | Small organic molecule |
Emp. Form. | C27H30N2O |
Mol. Mass. | 398.5399 |
SMILES | CC(C)CN1CC[C@]23Cc4nc5ccccc5cc4C[C@H]2[C@H]1Cc1ccc(O)cc31 |r,THB:3:4:20:29.23.22| |
Structure |
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