Reaction Details |
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Target | Mu-type opioid receptor |
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Ligand | BDBM50294428 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_575377 (CHEMBL1027051) |
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Ki | 12±n/a nM |
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Citation | Nagase, H; Osa, Y; Nemoto, T; Fujii, H; Imai, M; Nakamura, T; Kanemasa, T; Kato, A; Gouda, H; Hirono, S Design and synthesis of novel delta opioid receptor agonists and their pharmacologies. Bioorg Med Chem Lett19:2792-5 (2009) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Mu-type opioid receptor |
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Name: | Mu-type opioid receptor |
Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 44503.11 |
Organism: | Rattus norvegicus (rat) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. |
Residue: | 398 |
Sequence: | MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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BDBM50294428 |
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n/a |
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Name | BDBM50294428 |
Synonyms: | CHEMBL552308 | SN-28 |
Type | Small organic molecule |
Emp. Form. | C24H24N2O |
Mol. Mass. | 356.4602 |
SMILES | CN1CC[C@]23Cc4nc5ccccc5cc4C[C@H]2[C@H]1Cc1ccc(O)cc31 |r,THB:0:1:17:26.20.19| |
Structure |
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