| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50296869 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_580496 (CHEMBL1052523) |
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| Ki | 1790±n/a nM |
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| Citation |  Li, F; Gaob, L; Yin, C; Chen, J; Liu, J; Xie, X; Zhang, A Synthesis and opioid receptor activity of indolopropellanes. Bioorg Med Chem Lett19:4603-6 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM50296869 |
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| n/a |
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| Name | BDBM50296869 |
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| Synonyms: | (1S,13R)-22-(cyclopropylmethyl)-10-methyl-10,22-diazahexacyclo[11.7.4.0^{1,13}.0^{3,11}.0^{4,9}.0^{14,19}]tetracosa-3(11),4(9),5,7,14(19),15,17-heptaen-16-ol | CHEMBL558135 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H30N2O |
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| Mol. Mass. | 398.5399 |
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| SMILES | Cn1c2C[C@@]34CCN(CC5CC5)C[C@@]3(Cc3ccc(O)cc43)Cc2c2ccccc12 |r| |
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| Structure | 
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