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TargetCarbonic anhydrase 15
LigandBDBM50300204
Substrate/Competitorn/a
Meas. Tech.ChEMBL_592895
Ki 461±n/a nM
Citation Temperini CInnocenti AScozzafava AParkkila SSupuran CT The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors. J Med Chem 53:850-4 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 15
Name:Carbonic anhydrase 15
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:35484.02
Organism:Mus musculus
Description:ChEMBL_651955
Residue:324
Sequence:
MWALDFLLSFLLIQLAAQVDSSGTWCYDSQDPKCGPAHWKELAPACGGPTQSPINIDLRL
VQRDYTLKPFIFQGYDSAPQDPWVLENDGHTVLLRVNSCQQNCPAIRGAGLPSPEYRLLQ
LHFHWGSPGHQGSEHSLDEKHGSMEMHMVHMNTKYQSMEDARSQPDGFAILAVLLVEEDR
DNTNFSAIVSGLKNLSSPGVAVNLTSTFALASLLPSALRLLRYYRYSGSLTTPGCEPAVL
WTVFENTVPIGHAQVVQFQAVLQTGPPGLHPRPLTSNFRPQQPLGGRRISASPEASVRSS
VSTLPCLHLALVGLGVGLRLWQGP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50300204
n/a
NameBDBM50300204
Synonyms:(2R)-2-acetylamino-N-benzyl-3-methoxypropanamide | (R)-2-Acetylamino-N-benzyl-3-methoxy-propionamide | (R)-2-acetamido-N-benzyl-3-methoxypropanamide | (R)-N-benzyl 2-acetamido-3-methoxypropionamide | (R)-N-benzyl 2-acetamido-3-methoxypropionamide, | CHEMBL58323 | Erlosamide | LACOSAMIDE
TypeSmall organic molecule
Emp. Form.C13H18N2O3
Mol. Mass.250.2936
SMILESCOC[C@@H](NC(C)=O)C(=O)NCc1ccccc1 |r|
Structure
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