| Reaction Details |
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 | Report a problem with these data |
| Target | Serine racemase |
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| Ligand | BDBM50378532 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_594810 (CHEMBL1042549) |
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| IC50 | 370000±n/a nM |
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| Citation |  Hoffman, HE; Jirásková, J; Cígler, P; Sanda, M; Schraml, J; Konvalinka, J Hydroxamic acids as a novel family of serine racemase inhibitors: mechanistic analysis reveals different modes of interaction with the pyridoxal-5'-phosphate cofactor. J Med Chem52:6032-41 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine racemase |
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| Name: | Serine racemase |
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| Synonyms: | D-serine ammonia-lyase | D-serine dehydratase | L-serine ammonia-lyase | L-serine dehydratase | SRR_MOUSE | Srr |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36355.92 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1441161 |
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| Residue: | 339 |
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| Sequence: | MCAQYCISFADVEKAHINIQDSIHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGA
LNAIRGLIPDTPEEKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQA
YGASIVYCDPSDESREKVTQRIMQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDAL
VVPVGGGGMVAGIAITIKALKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGV
KSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWGRMKLLIEPTAGVALAAVLSQHFQT
VSPEVKNVCIVLSGGNVDLTSLNWVGQAERPAPYQTVSV
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| BDBM50378532 |
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| n/a |
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| Name | BDBM50378532 |
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| Synonyms: | CHEMBL569435 |
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| Type | Small organic molecule |
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| Emp. Form. | C3H6N2O4 |
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| Mol. Mass. | 134.0907 |
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| SMILES | ONC(=O)CC(=O)NO |
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| Structure | 
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