| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dihydropteroate synthase |
|---|
| Ligand | BDBM50378553 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_595738 (CHEMBL1045261) |
|---|
| IC50 | 19300±n/a nM |
|---|
| Citation |  Hevener, KE; Yun, MK; Qi, J; Kerr, ID; Babaoglu, K; Hurdle, JG; Balakrishna, K; White, SW; Lee, RE Structural studies of pterin-based inhibitors of dihydropteroate synthase. J Med Chem53:166-77 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Dihydropteroate synthase |
|---|
| Name: | Dihydropteroate synthase |
|---|
| Synonyms: | n/a |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 30967.84 |
|---|
| Organism: | Bacillus anthracis |
|---|
| Description: | ChEMBL_595739 |
|---|
| Residue: | 280 |
|---|
| Sequence: | MCSLKWDYDLRCGEYTLNLNEKTLIMGILNVTPDSFSDGGSYNEVDAAVRHAKEMRDEGA
HIIDIGGESTRPGFAKVSVEEEIKRVVPMIQAVSKEVKLPISIDTYKAEVAKQAIEAGAH
IINDIWGAKAEPKIAEVAAHYDVPIILMHNRDNMNYRNLMADMIADLYDSIKIAKDAGVR
DENIILDPGIGFAKTPEQNLEAMRNLEQLNVLGYPVLLGTSRKSFIGHVLDLPVEERLEG
TGATVCLGIEKGCEFVRVHDVKEMSRMAKMMDAMIGKGVK
|
|
|
|---|
| BDBM50378553 |
|---|
| n/a |
|---|
| Name | BDBM50378553 |
|---|
| Synonyms: | CHEMBL161604 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H15N5O5 |
|---|
| Mol. Mass. | 333.2994 |
|---|
| SMILES | Nc1nc(NCCCOc2ccc(cc2)C(O)=O)c(N=O)c(=O)[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
