Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetCarbonic anhydrase 15
LigandBDBM50303496
Substrate/Competitorn/a
Meas. Tech.ChEMBL_595961 (CHEMBL1044463)
Ki 7400±n/a nM
Citation Maresca, ATemperini, CPochet, LMasereel, BScozzafava, ASupuran, CT Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins. J Med Chem53:335-44 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 15
Name:Carbonic anhydrase 15
Synonyms:CAH15_MOUSE | Ca15 | Car15
Type:PROTEIN
Mol. Mass.:35484.02
Organism:Mus musculus
Description:ChEMBL_651955
Residue:324
Sequence:
MWALDFLLSFLLIQLAAQVDSSGTWCYDSQDPKCGPAHWKELAPACGGPTQSPINIDLRL
VQRDYTLKPFIFQGYDSAPQDPWVLENDGHTVLLRVNSCQQNCPAIRGAGLPSPEYRLLQ
LHFHWGSPGHQGSEHSLDEKHGSMEMHMVHMNTKYQSMEDARSQPDGFAILAVLLVEEDR
DNTNFSAIVSGLKNLSSPGVAVNLTSTFALASLLPSALRLLRYYRYSGSLTTPGCEPAVL
WTVFENTVPIGHAQVVQFQAVLQTGPPGLHPRPLTSNFRPQQPLGGRRISASPEASVRSS
VSTLPCLHLALVGLGVGLRLWQGP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50303496
n/a
NameBDBM50303496
Synonyms:6-(hydroxymethyl)-2H-chromen-2-one | CHEMBL571738
TypeSmall organic molecule
Emp. Form.C10H8O3
Mol. Mass.176.1687
SMILESOCc1ccc2oc(=O)ccc2c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: