| Reaction Details |
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 | Report a problem with these data |
| Target | Asparagine synthetase [glutamine-hydrolyzing] |
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| Ligand | BDBM50378579 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_601140 (CHEMBL1074555) |
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| Ki | 20000±n/a nM |
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| Citation |  Ikeuchi, H; Meyer, ME; Ding, Y; Hiratake, J; Richards, NG A critical electrostatic interaction mediates inhibitor recognition by human asparagine synthetase. Bioorg Med Chem17:6641-50 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Asparagine synthetase [glutamine-hydrolyzing] |
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| Name: | Asparagine synthetase [glutamine-hydrolyzing] |
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| Synonyms: | ASNS | ASNS_HUMAN | Asparagine synthetase | TS11 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 64373.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_851327 |
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| Residue: | 561 |
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| Sequence: | MCGIWALFGSDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRLAVVDPLFGMQ
PIRVKKYPYLWLCYNGEIYNHKKMQQHFEFEYQTKVDGEIILHLYDKGGIEQTICMLDGV
FAFVLLDTANKKVFLGRDTYGVRPLFKAMTEDGFLAVCSEAKGLVTLKHSATPFLKVEPF
LPGHYEVLDLKPNGKVASVEMVKYHHCRDVPLHALYDNVEKLFPGFEIETVKNNLRILFN
NAVKKRLMTDRRIGCLLSGGLDSSLVAATLLKQLKEAQVQYPLQTFAIGMEDSPDLLAAR
KVADHIGSEHYEVLFNSEEGIQALDEVIFSLETYDITTVRASVGMYLISKYIRKNTDSVV
IFSGEGSDELTQGYIYFHKAPSPEKAEEESERLLRELYLFDVLRADRTTAAHGLELRVPF
LDHRFSSYYLSLPPEMRIPKNGIEKHLLRETFEDSNLIPKEILWRPKEAFSDGITSVKNS
WFKILQEYVEHQVDDAMMANAAQKFPFNTPKTKEGYYYRQVFERHYPGRADWLSHYWMPK
WINATDPSARTLTHYKSAVKA
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| BDBM50378579 |
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| n/a |
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| Name | BDBM50378579 |
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| Synonyms: | CHEMBL1627258 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H22N7O9PS |
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| Mol. Mass. | 495.405 |
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| SMILES | CS(=O)(CC(=N)C(O)=O)NP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| |
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| Structure | 
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