| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50304403 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_603130 (CHEMBL1038852) |
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| Ki | 2070±n/a nM |
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| Citation |  Schulze, M; Müller, FK; Mason, JM; Görls, H; Lehmann, J; Enzensperger, C Dibenzazecine scaffold rebuilding--is the flexibility always essential for high dopamine receptor affinities? Bioorg Med Chem17:6898-907 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 49303.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21728 |
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| Residue: | 446 |
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| Sequence: | MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
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| BDBM50304403 |
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| n/a |
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| Name | BDBM50304403 |
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| Synonyms: | 6-Methyl-5,6,7,8,9,14-hexahydrodibenzo[c,f]azecin-11-ol | CHEMBL596179 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21NO |
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| Mol. Mass. | 267.3654 |
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| SMILES | CN1CCCc2cc(O)ccc2Cc2ccccc2C1 |
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| Structure | 
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