| Reaction Details |
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 | Report a problem with these data |
| Target | Myelin-associated glycoprotein |
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| Ligand | BDBM50327098 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_611883 (CHEMBL1070838) |
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| Kd | 17600±n/a nM |
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| Citation |  Mesch, S; Moser, D; Strasser, DS; Kelm, A; Cutting, B; Rossato, G; Vedani, A; Koliwer-Brandl, H; Wittwer, M; Rabbani, S; Schwardt, O; Kelm, S; Ernst, B Low molecular weight antagonists of the myelin-associated glycoprotein: synthesis, docking, and biological evaluation. J Med Chem53:1597-615 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Myelin-associated glycoprotein |
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| Name: | Myelin-associated glycoprotein |
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| Synonyms: | MAG_MOUSE | Mag | Siglec-4a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 69368.91 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_663794 |
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| Residue: | 627 |
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| Sequence: | MIFLATLPLFWIMISASRGGHWGAWMPSTISAFEGTCVSIPCRFDFPDELRPAVVHGVWY
FNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSTLSPELGGKYYFRGD
LGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGL
GEPTVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQAAFPNTTLQFEGYASLDVKYPP
VIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGMVLREAVAKSLYLDLEEVTPGED
GVYACLAENAYGQDNRTVELSVMYAPWKPTVNGTVVAVEGETVSILCSTQSNPDPILTIF
KEKQILATVIYESQLQLELPAVTPEDDGEYWCVAENQYGQRATAFNLSVEFAPIILLESH
CAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNETEREFVYSERSGLLLTSILTIRGQA
QAPPRVICTSRNLYGTQSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKK
NVTESSSFSGGDNPHVLYSPEFRISGAPDKYESEKQRLGSERRLLGLRGESPELDLSYSH
SDLGKRPTKDSYTLTEELAEYAEIRVK
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| BDBM50327098 |
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| n/a |
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| Name | BDBM50327098 |
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| Synonyms: | CHEMBL1254099 | sodium(2R,4S,5R,6R)-5-acetamido-6-((1R,2R)-3-benzamido-1,2-dihydroxypropyl)-2-(benzyloxy)-4-hydroxytetrahydro-2H-pyran-2-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29N2O9 |
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| Mol. Mass. | 501.5063 |
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| SMILES | CC(=O)N[C@@H]1[C@@H](O)C[C@@](OCc2ccccc2)(O[C@H]1[C@H](O)[C@H](O)CNC(=O)c1ccccc1)C([O-])=O |r| |
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| Structure | 
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