| Reaction Details |
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 | Report a problem with these data |
| Target | Galanin receptor type 1 |
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| Ligand | BDBM50415433 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_610349 (CHEMBL1072081) |
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| Ki | 34200±n/a nM |
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| Citation |  Robertson, CR; Scholl, EA; Pruess, TH; Green, BR; White, HS; Bulaj, G Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic delivery. J Med Chem53:1871-5 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Galanin receptor type 1 |
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| Name: | Galanin receptor type 1 |
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| Synonyms: | GAL1-R | GALNR | GALNR1 | GALR1 | GALR1_HUMAN | Galanin R1 | Galanin receptor 1 | Galanin receptor type 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38976.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Galanin R1 GALR1 HUMAN::P47211 |
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| Residue: | 349 |
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| Sequence: | MELAVGNLSEGNASWPEPPAPEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLAR
SKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSML
VSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPVAYHQGLFHPR
ASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEA
SKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNP
IIYAFLSENFRKAYKQVFKCHIRKDSHLSDTKESKSRIDTPPSTNCTHV
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| BDBM50415433 |
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| n/a |
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| Name | BDBM50415433 |
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| Synonyms: | CHEMBL1187471 |
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| Type | Small organic molecule |
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| Emp. Form. | C51H60N10O11 |
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| Mol. Mass. | 989.0825 |
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| SMILES | COC(=O)[C@H](CCCCN)NC(=O)[C@]1(C)NC(=O)c2nc(oc2C)[C@@](C)(NC(=O)c2nc(oc2C)[C@@](C)(NC(=O)c2nc1oc2C)C(=O)NCC1CCCCC1)C(=O)NC1c2ccccc2-c2ccccc12 |r| |
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| Structure | 
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