| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 6 |
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| Ligand | BDBM4374 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_613334 (CHEMBL1074271) |
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| Ki | 6720±n/a nM |
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| Citation |  Innocenti, A; Beyza Oztürk Sarikaya, S; Gülçin, I; Supuran, CT Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. Bioorg Med Chem18:2159-64 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 6 |
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| Name: | Carbonic anhydrase 6 |
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| Synonyms: | CA-VI | CA6 | CAH6_HUMAN | Carbonate dehydratase VI | Carbonic Anhydrase VI | Carbonic anhydrase | Carbonic anhydrase 6 | Carbonic anhydrase 6 (CA VI) | Carbonic anhydrase 6 (CA-VI) | Carbonic anhydrase VI (CA VI) | Salivary carbonic anhydrase | Secreted carbonic anhydrase |
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| Type: | Enzyme |
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| Mol. Mass.: | 35371.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P23280 |
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| Residue: | 308 |
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| Sequence: | MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYN
PSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSE
ISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNF
ISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLS
RTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEIL
DYLRRALN
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| BDBM4374 |
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| n/a |
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| Name | BDBM4374 |
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| Synonyms: | (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid | (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid (8) | CHEMBL66879 | p-Coumaric Acid | p-Hydroxycinnamic acid (p-HCA) | p-hydroxycinnamic acid | p-hydroxycinnamic acid (M4) |
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| Type | Small organic molecule |
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| Emp. Form. | C9H8O3 |
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| Mol. Mass. | 164.158 |
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| SMILES | OC(=O)\C=C\c1ccc(O)cc1 |
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| Structure | 
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