| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2a |
|---|
| Ligand | BDBM50308508 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_613367 (CHEMBL1068174) |
|---|
| Ki | 3750±n/a nM |
|---|
| Citation |  Scheiff, AB; Yerande, SG; El-Tayeb, A; Li, W; Inamdar, GS; Vasu, KK; Sudarsanam, V; Müller, CE 2-Amino-5-benzoyl-4-phenylthiazoles: Development of potent and selective adenosine A1 receptor antagonists. Bioorg Med Chem18:2195-203 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2a |
|---|
| Name: | Adenosine receptor A2a |
|---|
| Synonyms: | AA2AR_CAVPO | ADENOSINE A2 | ADORA2A | Adenosine A2a receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44955.08 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | ADENOSINE A2 0 GUINEA PIG::P46616 |
|---|
| Residue: | 409 |
|---|
| Sequence: | MSSSVYITVELVIAVLAILGNVLVCWAVWINSNLQNVTNYFVVSLAAADIAVGVLAIPFA
ITISTGFCAACHGCLFFACFVLVLTQSSIFSLLTITIDRYIAIRIPLRYNGLVTCTRAKG
IIAICWVLSFAIGLTPMLGWNNCSQPKGDKNHSESCDEGQVTCLFEDVVPMNYMVYYNFF
AFVLVPLLLMLGIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHPAKSLAIIVGLFA
LCCLPLNIINCFTFFCPECDHAPPWLMYLTIILSHGNSVVNPLIYAYRIREFRQTFRKII
RSHILRRRELFKAGGTSARASAAHSPEGEQVSLRLNGHPPGVWANGSALRPEQRPNGYVL
GLVSGRSAQRSHGDASLSDVELLSHEHKGTCPESPSLEDPPAHGGAGVS
|
|
|
|---|
| BDBM50308508 |
|---|
| n/a |
|---|
| Name | BDBM50308508 |
|---|
| Synonyms: | CHEMBL589549 | N-((1R,2S,4S)-bicyclo[2.2.1]heptan-2-yl)-9-methyl-9H-purin-6-amine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H17N5 |
|---|
| Mol. Mass. | 243.3076 |
|---|
| SMILES | Cn1cnc2c(N[C@H]3C[C@H]4CC[C@@H]3C4)ncnc12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
