| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50097431 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_613353 (CHEMBL1074290) |
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| Ki | 76±n/a nM |
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| Citation |  Scheiff, AB; Yerande, SG; El-Tayeb, A; Li, W; Inamdar, GS; Vasu, KK; Sudarsanam, V; Müller, CE 2-Amino-5-benzoyl-4-phenylthiazoles: Development of potent and selective adenosine A1 receptor antagonists. Bioorg Med Chem18:2195-203 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50097431 |
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| n/a |
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| Name | BDBM50097431 |
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| Synonyms: | 4-Methoxy-N-(4-phenyl-thiazol-2-yl)-benzamide | 4-Methoxy-N-(4-phenyl-thiazol-2-yl)-benzamide(LUF5433) | 4-methoxy-N-(4-phenylthiazol-2-yl)benzamide | CHEMBL60156 | LUF-5433 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N2O2S |
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| Mol. Mass. | 310.37 |
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| SMILES | COc1ccc(cc1)C(=O)Nc1nc(cs1)-c1ccccc1 |
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| Structure | 
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