| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50309532 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_609767 (CHEMBL1069385) |
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| Ki | >10000±n/a nM |
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| Citation |  Lange, JH; van der Neut, MA; Wals, HC; Kuil, GD; Borst, AJ; Mulder, A; den Hartog, AP; Zilaout, H; Goutier, W; van Stuivenberg, HH; van Vliet, BJ Synthesis and SAR of novel imidazoles as potent and selective cannabinoid CB2 receptor antagonists with high binding efficiencies. Bioorg Med Chem Lett20:1084-9 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52868.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21554 |
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| Residue: | 472 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50309532 |
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| n/a |
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| Name | BDBM50309532 |
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| Synonyms: | CHEMBL603476 | N-(((cis)-6,6-dimethylbicyclo[3.1.1]heptan-3-yl)methyl)-5-methyl-1-phenyl-1H-imidazole-4-carboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C21H27N3O |
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| Mol. Mass. | 337.4586 |
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| SMILES | Cc1c(ncn1-c1ccccc1)C(=O)NC[C@H]1C[C@@H]2C[C@H](C1)C2(C)C |r| |
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| Structure | 
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