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TargetVesicular acetylcholine transporter
LigandBDBM50039613
Substrate/Competitorn/a
Meas. Tech.ChEMBL_627490
Ki 0.055±n/a nM
Citation Efange SMKhare ABvon Hohenberg KMach RHParsons SMTu Z Synthesis and in vitro biological evaluation of carbonyl group-containing inhibitors of vesicular acetylcholine transporter. J Med Chem 53:2825-35 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Vesicular acetylcholine transporter
Name:Vesicular acetylcholine transporter
Synonyms:TorVAChT | VAChT
Type:PROTEIN
Mol. Mass.:56111.93
Organism:Torpedo californica
Description:ChEMBL_1503355
Residue:515
Sequence:
MGVTMAVGLAKAAMGKISSAIGERSKRISGAMNEPRRKRKILLVIVCIAMLLDNMLYMVI
VPIIPNYLETIRTYKLVYITTPSNGTNGSLLNSTQRAVLERNPNANEDIQIGVLFASKAI
LQLLSNPFTGTFIDRVGYDIPLLIGLTIMFFSTITFAFGESYAVLFAARSLQGLGSAFAD
TSGIAMIADKYTEESERTQALGIALAFISFGSLVAPPFGGVLYQFAGKWVPFLVLSFVCL
LDGILLLMVVTPFASRTRENMLQGTPIYKLMIDPYIAVVAGALTTCNIPLAFLEPTISNW
MKKTMNASEWQMGITWLPAFFPHILGVYITVKLAAKYPNYQWFYGAVGLVIIGASSCTIP
ACRNFEELIIPLCALCFGIALVDTALLPTLAFLVDIRYVSVYGSVYAIADISYSVAYALG
PIMAGQIVHDLGFVQLNLGMGLVNILYAPALLFLRNVCQMKPSLSERNILLEEGPKGLYD
TIIMEERKAAKEPHGSSSGNHSVHAVLSDQEGYSE
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  Blast E-value cutoff:
BDBM50039613
n/a
NameBDBM50039613
Synonyms:(2R,3R)-3-(4-Phenyl-piperidin-1-yl)-1,2,3,4-tetrahydro-naphthalen-2-ol | Benzovesamicol | CHEMBL87379 | trans-3-(4-phenylpiperidin-1-yl)-1,2,3,4-tetrahydronaphthalen-2-ol
TypeSmall organic molecule
Emp. Form.C21H25NO
Mol. Mass.307.4293
SMILESO[C@@H]1Cc2ccccc2C[C@H]1N1CCC(CC1)c1ccccc1 |r|
Structure
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