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TargetNeuraminidase
LigandBDBM50320769
Substrate/Competitorn/a
Meas. Tech.ChEMBL_639158
IC50 6500±n/a nM
Citation Wen WHWang SYTsai KCCheng YSYang ASFang JMWong CH Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses. Bioorg Med Chem 18:4074-84 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Neuraminidase
Name:Neuraminidase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:49673.59
Organism:Influenza A virus
Description:ChEMBL_1347422
Residue:453
Sequence:
MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGSITYKVVA
GQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQ
GALLNDKHSRGTFKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGIS
GPDDGAVAVLKYNGIITETIKSWRKNILRTQESECTCVNGSCFTIMTDGPSDGLASYKIF
KIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYKIGY
ICSGVFGDNPRPKDGTGSCGPVSADGANGVKGFSYKYGNGVWIGRTKSDSSRHGFEMIWD
PNGWTETDSRFSMRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGLPEENAI
WTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50320769
n/a
NameBDBM50320769
Synonyms:5-Acetamido-2,6-anhydro-4-{N-[3-(4-methylpiperazinocarbonyl)propyl]guanidino}-3,4,5-trideoxy-D-glycero-Dgalacto-non-2-enonic acid | CHEMBL1164463
TypeSmall organic molecule
Emp. Form.C21H36N6O8
Mol. Mass.500.5459
SMILESCN1CCN(CC1)C(=O)CCCN([C@H]1C=C(O[C@@H]([C@H](O)[C@H](O)CO)[C@@H]1NC(C)=O)C(O)=O)C(N)=N |r,c:15|
Structure
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