| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50321024 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_639432 (CHEMBL1168405) |
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| Ki | 15±n/a nM |
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| Citation |  Yamaotsu, N; Fujii, H; Nagase, H; Hirono, S Identification of the three-dimensional pharmacophore of kappa-opioid receptor agonists. Bioorg Med Chem18:4446-52 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM50321024 |
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| n/a |
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| Name | BDBM50321024 |
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| Synonyms: | (1R,2S,4R,5S)-dimethyl 3,7-dimethyl-9-oxo-2,4-di(pyridin-2-yl)-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarboxylate | CHEMBL1163522 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26N4O5 |
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| Mol. Mass. | 438.4763 |
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| SMILES | COC(=O)[C@@]12CN(C)C[C@]([C@H](N(C)[C@H]1c1ccccn1)c1ccccn1)(C(=O)OC)C2=O |r,THB:31:30:10.11.13:8.5.6| |
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| Structure | 
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