| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 1 |
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| Ligand | BDBM50321584 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_639731 (CHEMBL1175620) |
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| Ki | 600±n/a nM |
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| Citation |  Thalji, RK; Aiyar, N; Davenport, EA; Erhardt, JA; Kallal, LA; Morrow, DM; Senadhi, S; Burns-Kurtis, CL; Marino, JP Benzofuran-substituted urea derivatives as novel P2Y(1) receptor antagonists. Bioorg Med Chem Lett20:4104-7 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 1 |
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| Name: | P2Y purinoceptor 1 |
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| Synonyms: | ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42090.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47900 |
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| Residue: | 373 |
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| Sequence: | MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYIL
VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFG
DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVV
VAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI
VRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFND
RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLN
ILPEFKQNGDTSL
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| BDBM50321584 |
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| n/a |
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| Name | BDBM50321584 |
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| Synonyms: | 1-(2-(2-isopropylphenyl)benzofuran-7-yl)-3-(4-(trifluoromethoxy)phenyl)urea | CHEMBL1172139 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H21F3N2O3 |
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| Mol. Mass. | 454.441 |
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| SMILES | CC(C)c1ccccc1-c1cc2cccc(NC(=O)Nc3ccc(OC(F)(F)F)cc3)c2o1 |
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| Structure | 
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