| Reaction Details |
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 | Report a problem with these data |
| Target | Methionine aminopeptidase 2 |
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| Ligand | BDBM50078834 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_639878 (CHEMBL1173893) |
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| IC50 | 13300±n/a nM |
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| Citation |  Altmeyer, MA; Marschner, A; Schiffmann, R; Klein, CD Subtype-selectivity of metal-dependent methionine aminopeptidase inhibitors. Bioorg Med Chem Lett20:4038-44 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Methionine aminopeptidase 2 |
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| Name: | Methionine aminopeptidase 2 |
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| Synonyms: | Initiation factor 2-associated 67 kDa glycoprotein | MAP 2 | MAP2_HUMAN | METAP2 | MNPEP | MetAP 2 | Methionine aminopeptidase 2 (MetAP2) | Methionine aminopeptidases (HsMetAP2) | P67EIF2 | Peptidase M 2 | p67 |
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| Type: | Enzyme |
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| Mol. Mass.: | 52884.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50579 |
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| Residue: | 478 |
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| Sequence: | MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
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| BDBM50078834 |
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| n/a |
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| Name | BDBM50078834 |
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| Synonyms: | 2-(pyridin-2-yl)-1H-benzo[d]imidazole | 2-pyridin-2-yl-1H-benzoimidazole | CHEMBL72683 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H9N3 |
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| Mol. Mass. | 195.22 |
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| SMILES | c1ccc(nc1)-c1nc2ccccc2[nH]1 |
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| Structure | 
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