| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM50321873 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_642098 (CHEMBL1176402) |
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| Ki | 126±n/a nM |
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| Citation |  Cummings, DF; Canseco, DC; Sheth, P; Johnson, JE; Schetz, JA Synthesis and structure-affinity relationships of novel small molecule natural product derivatives capable of discriminating between serotonin 5-HT1A, 5-HT2A, 5-HT2C receptor subtypes. Bioorg Med Chem18:4783-92 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A |
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| Type: | undefined |
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| Mol. Mass.: | 52607.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P28223 |
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| Residue: | 471 |
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| Sequence: | MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
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| BDBM50321873 |
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| n/a |
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| Name | BDBM50321873 |
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| Synonyms: | 4-Bromo-5-methyl-2,3-dihydro-indole-1-carboxylic acid pyridin-3-ylamide | 4-bromo-5-methyl-N-(pyridin-3-yl)indoline-1-carboxamide | CHEMBL42463 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14BrN3O |
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| Mol. Mass. | 332.195 |
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| SMILES | Cc1ccc2N(CCc2c1Br)C(=O)Nc1cccnc1 |
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| Structure | 
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