| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cyclin-A2 |
|---|
| Ligand | BDBM50378816 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_660574 (CHEMBL1250282) |
|---|
| IC50 | 12000±n/a nM |
|---|
| Citation |  Sridhar, J; Akula, N; Pattabiraman, N Selectivity and potency of cyclin-dependent kinase inhibitors. AAPS J8:204-21 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cyclin-A2 |
|---|
| Name: | Cyclin-A2 |
|---|
| Synonyms: | CCN1 | CCNA | CCNA1 | CCNA2 | CCNA2_HUMAN | Cyclin A | Cyclin-A |
|---|
| Type: | Enzyme Subunit |
|---|
| Mol. Mass.: | 48550.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P20248 |
|---|
| Residue: | 432 |
|---|
| Sequence: | MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRG
LAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKI
EREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIILEDEKPVSVNEVPDYHE
DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID
RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLK
VLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAF
HLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHG
VSLLNPPETLNL
|
|
|
|---|
| BDBM50378816 |
|---|
| n/a |
|---|
| Name | BDBM50378816 |
|---|
| Synonyms: | CHEMBL1241138 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H55N13O7 |
|---|
| Mol. Mass. | 745.8727 |
|---|
| SMILES | [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](-[#6])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
