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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sodium- and chloride-dependent glycine transporter 2 | ||
| Ligand | BDBM50335012 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_702706 (CHEMBL1657780) | ||
| IC50 | 780±n/a nM | ||
| Citation |  Kohara, A; Doihara, H; Saita, K; Aota, M Synthesis and biological evaluation of 3-biphenyl-4-yl-4-phenyl-4H-1,2,4-triazoles as novel glycine transporter 1 inhibitors. J Med Chem54:387-91 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sodium- and chloride-dependent glycine transporter 2 | |||
| Name: | Sodium- and chloride-dependent glycine transporter 2 | ||
| Synonyms: | Glycine transporter 2 | Glyt2 | SC6A5_RAT | Slc6a5 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 87845.43 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_980598 | ||
| Residue: | 799 | ||
| Sequence: |
| ||
| BDBM50335012 | |||
| n/a | |||
| Name | BDBM50335012 | ||
| Synonyms: | 3-Biphenyl-4-yl-5-methyl-4-(2-methylphenyl)-4H-1,2,4-triazole | CHEMBL1649958 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H19N3 | ||
| Mol. Mass. | 325.4064 | ||
| SMILES | Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1C |(32.05,-21.71,;30.58,-21.23,;30.11,-19.76,;28.57,-19.76,;28.09,-21.22,;26.77,-22,;26.77,-23.54,;25.44,-24.32,;24.11,-23.55,;24.1,-22.02,;25.42,-21.24,;22.78,-24.32,;21.45,-23.56,;20.12,-24.33,;20.12,-25.87,;21.45,-26.64,;22.79,-25.87,;29.34,-22.13,;29.34,-23.66,;28,-24.43,;28,-25.97,;29.33,-26.74,;30.67,-25.97,;30.66,-24.43,;32,-23.66,)| | ||
| Structure | 
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