| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier family 15 member 2 |
|---|
| Ligand | BDBM50350470 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_762551 (CHEMBL1817008) |
|---|
| Ki | 11000000±n/a nM |
|---|
| Citation |  Pedretti, A; De Luca, L; Marconi, C; Regazzoni, L; Aldini, G; Vistoli, G Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping. Bioorg Med Chem19:4544-51 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Solute carrier family 15 member 2 |
|---|
| Name: | Solute carrier family 15 member 2 |
|---|
| Synonyms: | Kidney H(+)/peptide cotransporter | Oligopeptide transporter, kidney isoform | PEPT2 | Peptide transporter 2 | S15A2_HUMAN | SLC15A2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 81795.62 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_762551 |
|---|
| Residue: | 729 |
|---|
| Sequence: | MNPFQKNESKETLFSPVSIEEVPPRPPSPPKKPSPTICGSNYPLSIAFIVVNEFCERFSY
YGMKAVLILYFLYFLHWNEDTSTSIYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLV
YVLGHVIKSLGALPILGGQVVHTVLSLIGLSLIALGTGGIKPCVAAFGGDQFEEKHAEER
TRYFSVFYLSINAGSLISTFITPMLRGDVQCFGEDCYALAFGVPGLLMVIALVVFAMGSK
IYNKPPPEGNIVAQVFKCIWFAISNRFKNRSGDIPKRQHWLDWAAEKYPKQLIMDVKALT
RVLFLYIPLPMFWALLDQQGSRWTLQAIRMNRNLGFFVLQPDQMQVLNPLLVLIFIPLFD
FVIYRLVSKCGINFSSLRKMAVGMILACLAFAVAAAVEIKINEMAPAQPGPQEVFLQVLN
LADDEVKVTVVGNENNSLLIESIKSFQKTPHYSKLHLKTKSQDFHFHLKYHNLSLYTEHS
VQEKNWYSLVIREDGNSISSMMVKDTESRTTNGMTTVRFVNTLHKDVNISLSTDTSLNVG
EDYGVSAYRTVQRGEYPAVHCRTEDKNFSLNLGLLDFGAAYLFVITNNTNQGLQAWKIED
IPANKMSIAWQLPQYALVTAGEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTIAVGNIIV
LVVAQFSGLVQWAEFILFSCLLLVICLIFSIMGYYYVPVKTEDMRGPADKHIPHIQGNMI
KLETKKTKL
|
|
|
|---|
| BDBM50350470 |
|---|
| n/a |
|---|
| Name | BDBM50350470 |
|---|
| Synonyms: | CEFEPIME | Maxipime |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H24N6O5S2 |
|---|
| Mol. Mass. | 480.561 |
|---|
| SMILES | CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(C[N+]3(C)CCCC3)=C(N2C1=O)C([O-])=O)c1csc(N)n1 |r,c:19| |
|---|
| Structure | 
|
|---|
Search and Browse
