| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50354109 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_770979 (CHEMBL1838218) |
|---|
| Ki | 44000±n/a nM |
|---|
| Citation |  Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Synthesis and biological investigation of potential atypical antipsychotics with a tropane core. Part 1. Eur J Med Chem46:4474-88 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 50931.60 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P61169 |
|---|
| Residue: | 444 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
|
|
|
|---|
| BDBM50354109 |
|---|
| n/a |
|---|
| Name | BDBM50354109 |
|---|
| Synonyms: | CHEMBL1836050 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H23ClN2O3 |
|---|
| Mol. Mass. | 374.861 |
|---|
| SMILES | COc1ccc(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 |r,TLB:11:12:19:15.16| |
|---|
| Structure | 
|
|---|
Search and Browse
