| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50354091 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_770979 (CHEMBL1838218) |
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| Ki | 26.3±n/a nM |
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| Citation |  Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Synthesis and biological investigation of potential atypical antipsychotics with a tropane core. Part 1. Eur J Med Chem46:4474-88 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50354091 |
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| n/a |
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| Name | BDBM50354091 |
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| Synonyms: | CHEMBL1836044 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26N2O4 |
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| Mol. Mass. | 370.4421 |
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| SMILES | COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccco2)c1OC |r,TLB:9:10:17:13.14| |
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| Structure | 
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