| Reaction Details |
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 | Report a problem with these data |
| Target | Low molecular weight phosphotyrosine protein phosphatase |
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| Ligand | BDBM50379833 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_809717 (CHEMBL2016028) |
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| IC50 | 11700±n/a nM |
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| Citation |  Ottanà, R; Maccari, R; Amuso, S; Wolber, G; Schuster, D; Herdlinger, S; Manao, G; Camici, G; Paoli, P New 4-[(5-arylidene-2-arylimino-4-oxo-3-thiazolidinyl)methyl]benzoic acids active as protein tyrosine phosphatase inhibitors endowed with insulinomimetic effect on mouse C2C12 skeletal muscle cells. Eur J Med Chem50:332-43 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Low molecular weight phosphotyrosine protein phosphatase |
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| Name: | Low molecular weight phosphotyrosine protein phosphatase |
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| Synonyms: | 3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c |
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| Type: | n/a |
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| Mol. Mass.: | 18042.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24666 |
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| Residue: | 158 |
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| Sequence: | MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRG
QSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSY
DPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
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| BDBM50379833 |
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| n/a |
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| Name | BDBM50379833 |
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| Synonyms: | CHEMBL2011707 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H22N2O4S |
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| Mol. Mass. | 494.561 |
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| SMILES | COc1ccc(cc1)\N=C1/S\C(=C/c2ccc3ccccc3c2)C(=O)N1Cc1ccc(cc1)C(O)=O |
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| Structure | 
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