| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostate-specific antigen |
|---|
| Ligand | BDBM50379839 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_809739 (CHEMBL2016158) |
|---|
| IC50 | 226±n/a nM |
|---|
| Citation |  Liang, G; Chen, X; Aldous, S; Pu, SF; Mehdi, S; Powers, E; Xia, T; Wang, R Human kallikrein 6 inhibitors with a para-amidobenzylanmine P1 group identified through virtual screening. Bioorg Med Chem Lett22:2450-5 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostate-specific antigen |
|---|
| Name: | Prostate-specific antigen |
|---|
| Synonyms: | APS | Gamma-seminoprotein | KLK3 | KLK3_HUMAN | Kallikrein-3 | P-30 antigen | PSA | Prostate specific antigen | Prostate-specific antigen | Semenogelase | Seminin |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 28747.53 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_959198 |
|---|
| Residue: | 261 |
|---|
| Sequence: | MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD
LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS
NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP
SLYTKVVHYRKWIKDTIVANP
|
|
|
|---|
| BDBM50379839 |
|---|
| n/a |
|---|
| Name | BDBM50379839 |
|---|
| Synonyms: | CHEMBL2011751 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H27NO8 |
|---|
| Mol. Mass. | 565.5694 |
|---|
| SMILES | Oc1ccc(C[C@H]2[C@H](N(C(=O)Oc3cccc(c3)C(=O)OCc3ccccc3)C2=O)C(=O)OCc2ccccc2)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
