| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Galactokinase |
|---|
| Ligand | BDBM50380339 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_813856 (CHEMBL2020225) |
|---|
| IC50 | 900±n/a nM |
|---|
| Citation |  Odejinmi, S; Rascon, R; Tang, M; Vankayalapati, H; Lai, K Structure-activity analysis and cell-based optimization of human galactokinase inhibitors. ACS Med Chem Lett2:667-672 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Galactokinase |
|---|
| Name: | Galactokinase |
|---|
| Synonyms: | GALK | GALK1 | GALK1_HUMAN | Galactokinase | Galactokinase (GALK) | Galactose kinase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 42271.26 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P51570 |
|---|
| Residue: | 392 |
|---|
| Sequence: | MAALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELM
TVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAA
PLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGM
PCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRR
RQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDY
RAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASA
APHAMRHIQEHYGGTATFYLSQAADGAKVLCL
|
|
|
|---|
| BDBM50380339 |
|---|
| n/a |
|---|
| Name | BDBM50380339 |
|---|
| Synonyms: | CHEMBL2017800 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H21N3O4S2 |
|---|
| Mol. Mass. | 455.55 |
|---|
| SMILES | Oc1ccc(O)c(c1)C1NC(=O)C(C#N)=C(SCc2cccc(c2)N2CCOCC2)S1 |t:15| |
|---|
| Structure | 
|
|---|
Search and Browse
